Abstract
We report a rare case of Plasma cell hyperplasia (PCH) of the Central Nervous System (CNS) in a 25 year old male involving the pachymeninges and brain parenchyma which was a diagnostic dilemma due to overlapping imaging features with other pathologies. On CT, there was white matter edema and gyral swelling in left parietoccipital region. The involved region showed ill-defined diffuse sheet like peripheral enhancement on post contrast CT, which was thought to be intraparencymal than pachymeningeal. On post contrast MR imaging, there was thick sheet like pachymeningeal enhancement with dural tail formation in addition to diffuse peripheral gyral enhancement and white matter edema in above location. Gross total excision of dural based lesion was done and histopathology revealed features of plasma cell hyperplasia. No evidence of recurrence was seen at six month follow-up.
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