Abstract

Khalid Shahzad1, Anum Ashfaq1*, Muhammad Atif Beg2, Tariq Hussain1, Uzma Batool2, Syed Yar Muhammad Shah3, Zala Ejaz4, Mahzaib Raza4, Ramshaw Waqar4 and Zunaira Habib4 Author Affiliations 1Resident General Medicine, Pakistan Atomic Energy Commission General Hospital, Pakistan 2Consultant General Medicine, Pakistan Atomic Energy Commission General Hospital, Pakistan 3Resident General Medicine, Ayub Teaching Hospital, Pakistan 4Resident General Medicine, Pakistan Atomic Energy Commission General Hospital, Pakistan Received: August 12, 2021 | Published: September 17, 2021 Corresponding author: Anum Ashfaq, Resident General Medicine, Pakistan Atomic Energy Commission General Hospital, Islamabad, Pakistan DOI: 10.26717/BJSTR.2021.38.006208

Highlights

  • Plasmodium vivax is one of the most widely distributed specie of genus plasmodium causing infection in humans with approximately 80 million new cases annually

  • Severe infection with P. vivax is extremely rare Kochar et al has reported a case of P. vivax presenting with severe infection leading to severe anemia, renal involvement and Acute Respiratory Distress Syndrome (ARDS) with multiorgan failure

  • About 85% of all the malarial cases in the world are due to Plasmodium falciparum with Plasmodium vivax on 2nd number. 90% of all the malarial deaths occur in Africa [3]

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Summary

Background

Plasmodium vivax is one of the most widely distributed specie of genus plasmodium causing infection in humans with approximately 80 million new cases annually. Pancytopenia is an extremely rare complication of P. vivax malaria with various proposed mechanisms including macroangiopathic hemolytic anemia, hemophagocytic syndrome and direct bone marrow suppression [1]. This is one such case of isolated vivax malaria presenting with pancytopenia. Patient was started on Intravenous Artesunate as she could not tolerate Oral anti-malarial. Her Hematologic parameters dropped further during her stay at the hospital with TLC to 2520/ microliter, Hb to 8.5 g/dl and platelets to 11000/ microliter. She became afebrile and her blood parameters normalized after 5 days. She was discharged with follow up test for G6PD assay after one week

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