Rare case of giant extra gastrointestinal stromal tumor of wild variant

Abstract

Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms of gastrointestinal tract. The interstitial cells of Cajal (pacemaker cells) act as normal counterpart of tumor. They are rare cancers with incidence of 1.5 in 100000. KIT and PDGFRA gene mutations are the most common pathogenetic causes, whereas a minority of GISTs do not harbour either of the mutations, referred to as wild type GISTs. A minority of cases are extra gastrointestinal (EGIST), arising from mesentry, omentum and retroperitoneum. We present a wild type EGIST measuring 32×24×15 cm and weighing approximately 6 kg.