Abstract
(Abstracted from Prenatal Diagn 2018;38(10):765–771) Noninvasive prenatal testing (NIPT) analyzes cell-free DNA (cfDNA) in maternal plasma, which is a combination of DNA from maternal cells and from placental cytotrophoblast. The technique of massively parallel sequencing (MPS) sequences and counts large numbers of unique, single-locus DNA fragments and assigns them to the chromosome of origin.
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