Abstract

We report a case of cholangiocarcinoma of the liver coexisting with a huge cyst. A 23-year-old woman came to Tottori University Hospital complaining of an upper-abdominal mass. Ultrasonography showed a huge cystic lesion in the left lobe of the liver. A CT scan revealed not only the multilocular cyst but a low density area in the liver adjoining the cyst. Percutaneous drainage of the cyst and 100% ethanol injection therapy were preferred because the lesion was initially judged to be benign. The low density area in the liver was larger in the follow-up CT scan, and was diagnosed as malignant by aspiration biopsy cytology. Laparotomy revealed a liver tumor with a cyst, and peritoneal and lymph node metastases. Palliative left lobectomy of the liver was performed, and the patient died 259 days after surgery. Histologic examination revealed cholangiocarcinoma of the poorly differentiated type. Surgery is highly recommended for such cystic lesions of the liver when malignancy has not been ruled out.

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