Rapidly enlarging giant facial mass: initial presentation of blastic plasmacytoid dendritic cell neoplasm

Gulsen Akoglu,Tekin Guney,Sibel Orhun Yavuz,Aydan Kilicarslan

doi:10.7241/ourd.20174.128

Abstract

Rapidly enlarging giant facial mass: initial presentation of blastic plasmacytoid dendritic cell neoplasm

Highlights

CASE REPORTBlastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematological malignancy
The disease was named as CD4+/CD56+ hematodermic neoplasm or NK cell lymphoma until immunophenotypic and gene expression features of the neoplastic cells showed the resemblance of plasmacytoid dendritic cells [1]
BPDCN usually presents with cutaneous lesions as nodules, bruise-like patches, and disseminated skin lesions

Summary

Introduction

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematological malignancy. The disease was named as CD4+/CD56+ hematodermic neoplasm or NK cell lymphoma until immunophenotypic and gene expression features of the neoplastic cells showed the resemblance of plasmacytoid dendritic cells (pDC) [1]. Skin involvement is usually present at the diagnosis [2]. We report an elderly patient having a diagnosis of BPDCN and details of clinicopathological features and the follow up observations.

Results

Conclusion