Abstract

To the Editor:— In the Feb. 26, 1955 issue ofThe Journal, page 719, W. T. Caraway describes a Rapid Turbidity Test for Diagnosis of Uremia and refers to the spot test by Patterson (Lancet1:1061, 1934) that was found unsatisfactory. In 1942, with Plotz and Reich, I devised (J. Lab. & Clin. Med.28:335, 1942) a modification of the Patterson spot test performed by dropping Ehrlich's aldehyde reagent (p-dimethylaminobenzaldehyde Kodak 0.5 gm., trichloracetic acid 100 gm., distilled water up to 100 ml.) on filter paper, placing a drop of blood on the still wet surface, and drying the paper over a desk or microscope lamp. A positive reaction in the presence of blood urea nitrogen levels of more than about 50 mg. per 100 cc. is indicated by a distinct yellow zone diffusing around the brown spot of coagulated blood. This test proved simple, speedy, and

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