Rapid synthesis and characterization of silver-loaded graphene oxide nanomaterials and their antibacterial applications.

Jiang Zhu,Chunyan Hu,Song Liu,Yuxiang Zhu,Hongpan Liu,Jie Gao,Haitao Ni,Jinxia Cai,Heshan Yang

doi:10.1098/rsos.201744

Jiang Zhu, Chunyan Hu + Show 7 more

Open Access

https://doi.org/10.1098/rsos.201744

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Abstract

With the promising potential application of Ag/graphene-based nanomaterials in medicine and engineering materials, the large-scale production has attracted great interest of researchers on the basis of green synthesis. In this study, water-soluble silver/graphene oxide (Ag/GO) nanomaterials were synthesized under ultrasound-assisted conditions. The structural characteristics of Ag/GO were confirmed by Fourier transform infrared spectroscopy, X-ray diffraction, transmission electron microscopy, scanning electron microscopy and energy dispersion spectroscopy, respectively. The results showed the silver particles (AgNPs) obtained by reduction were attached to the surface of GO, and there was a strong interaction between AgNPs and GO. The antibacterial activity was primarily evaluated by the plate method and hole punching method. Antibacterial tests indicated that Ag/GO could inhibit the growth of Gram-negative and Gram-positive bacteria, special for the Staphylococcus aureus.

Highlights

Metal nanoparticles (MNPs) have attracted much attention owing to their superior characteristics including large specific surface area, high physical stability, strong electron transfer ability and high light absorption, retaining many applications such as royalsocietypublishing.org/journal/rsos R
After treating by H2SO4, the surface of Graphene oxide (GO) contained many oxygen-containing functional groups, such as epoxy, hydroxyl, carbonyl and carboxylic acid groups. These functional groups can be used as negative active sites for metal cations [10]
The infrared and X-ray photoelectron spectrometer (XPS) indicated that there was a strong interaction between AgNPs and GO, so that AgNPs are well dispersed on the surface of the GO nanosheet

Summary

Introduction

Metal nanoparticles (MNPs) have attracted much attention owing to their superior characteristics including large specific surface area, high physical stability, strong electron transfer ability and high light absorption, retaining many applications such as royalsocietypublishing.org/journal/rsos R. Various MNPs have been investigated, especially silver 2 nanoparticles (AgNPs), which are unique compared to other MNPs because of their spectral antibacterial properties. Many researchers have investigated the release of silver ions (Ag+) from AgNPs, and AgNPs bind to enzymes in the thiol group and interfere with the respiratory chain of microorganisms, leading to cell damage and oxidative stress. Because of these characteristics, AgNPs are increasingly used as a general solution for antibacterial activity [3]. The instability of AgNPs will cause the particles to agglomerate and reduce the antibacterial activity. To improve the antibacterial properties of the material and minimize the adverse effects of AgNPs, it is very important to apply novel nanostructures as an alternative to decorative AgNPs

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