Rapid Spontaneous Regression of Bilateral Pseudotumor

Abstract

Purpose: To report a rare case of bilateral pseudotumor with a two-week rapid spontaneous regression Method: A 63-year-old man visited our clinic with a chief complaint of a headache and right ocular pain. An orbital computerized tomography (CT) scan revealed a roud mass with well-demarcated capsule-like boundaries located in the inferior part of both orbits. After a systemic evaluation to exclude a systemic malignancy, we performed excisional biopsy of the right orbital mass to make diagnosis. Result: The right orbital mass was not found at the time of surgery for an excisional biopsy. Instead, we took multiple small biopsies of orbital fat, inferior rectus muscle, and adjacent soft tissues. Histologic examination revealed a non-specific inflammatory reaction without the presence of tumor cells. There was a marked spontaneous regression of the mass in both orbits on an immediate follow-up orbital CT. The patient began steroid treatment for 12 weeks under the presumptive diagnosis of bilateral pseudotumor. There was no evidence of recurrence at the eight-month follow-up.