Abstract
Ophiopogon japonicus (Thunb.) Ker-Gawl (Liliaceae), which is named as "Maidong" in China, is widely used in traditional Chinese medicine for treating fever, cough, inflammation, epistaxis, constipation, respiratory disease and gastrointestinal disorders. However, the systematic analysis of chemical constituents of O. japonicus has not been well established because of the complexity and trace. In this paper, an effective and reliable high-performance liquid chromatography coupled to electrospray ionization and quadrupole time-of-flight mass spectrometry method was successfully developed to separate and identify the chemical constituents from O. japonicus. As a result, a total of 30 compounds including steroidal saponins, homoisoflavonoids, allylbenzene, cholest and cryptomeridiol were screened or tentatively identified. Of them, three new steroidal saponins were found and tentatively characterized in O. japonicus. This study provides a meaningful material basis for further quality control and pharmacological research.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
