Rapid Regression of White Matter Changes in Hypoglycemic Encephalopathy

Abstract

Hypoglycemia is caused by imbalance between glucose supply and glucose utilization. It is apt to be caused in diabetic patients as a side effect of excessive insulin and sulfonylurea uses. When hypoglycemic injury affects brain tissue and induces neurologic abnormalities, it is called hypoglycemic encephalopathy. There is a report of DWI image changes from subcortical white matter lesions to cortical lesions in hypoglycemic encephalopathy, but it took several days for the changes (1). We present a case of hypoglycemic encephalopathy, showing rapid changes and uncommon findings on sequential MRI examinations.