Rapid Quantitative Detection of Deltamethrin in Corydalis yanhusuo by SERS Coupled with Multi-Walled Carbon Nanotubes.

Hui Zhang,Pengcheng Nie,Yong He,Xiaoxi Liu,Xuping Feng,Zhengyan Xia

doi:10.3390/molecules25184081

Abstract

With the increase in demand, artificially planting Chinese medicinal materials (CHMs) has also increased, and the ensuing pesticide residue problems have attracted more and more attention. An optimized quick, easy, cheap, effective, rugged and safe (QuEChERS) method with multi-walled carbon nanotubes as dispersive solid-phase extraction sorbents coupled with surface-enhanced Raman spectroscopy (SERS) was first proposed for the detection of deltamethrin in complex matrix Corydalis yanhusuo. Our results demonstrate that using the optimized QuEChERS method could effectively extract the analyte and reduce background interference from Corydalis. Facile synthesized gold nanoparticles with a large diameter of 75 nm had a strong SERS enhancement for deltamethrin determination. The best prediction model was established with partial least squares regression of the SERS spectra ranges of 545~573 cm−1 and 987~1011 cm−1 with a coefficient of determination (R2) of 0.9306, a detection limit of 0.484 mg/L and a residual predictive deviation of 3.046. In summary, this article provides a new rapid and effective method for the detection of pesticide residues in CHMs.

Highlights

Chinese herbal medicines (CHMs) have played an important role in clinical therapy for many diseases, especially as a valuable, readily available resource for healthcare for thousands of years.For example, the alkaloids in Corydalis
The results show that the best predictive effect in the deltamethrin quantitative analysis model was the PLS model based on the spectral data of a combination of the two peak bands, and the correlation coefficient of determination (R2 ), root mean square error for prediction (RMSEP) and residual predictive deviation (RPD) were 0.9306, 0.710 and 3.046, respectively
The SERS technology with facile synthesized AuNPs as the substrate coupled with the optimized QuECHERS pretreatment method with multi-walled carbon nanotubes (MWCNTs) as the purification material realized the quantitative detection of deltamethrin in CHMs Corydalis

Summary

Introduction

Chinese herbal medicines (CHMs) have played an important role in clinical therapy for many diseases, especially as a valuable, readily available resource for healthcare for thousands of years.For example, the alkaloids in Corydalis Chinese herbal medicines (CHMs) have played an important role in clinical therapy for many diseases, especially as a valuable, readily available resource for healthcare for thousands of years. CHMs in traditional medical treatment as well as modern Western medical treatment for cancer, asthma, malaria, and other diseases [1,2]. The commercial cultivation of CHMs leads to the frequent application of diverse pesticides to prevent, repel or mitigate the effects of pests, which causes environmental pollution and threatens human health [3,4]. With the wide application of corydalis in the medical field, it is crucial to examine pesticide residues for safety. Deltamethrin is a widely used pyrethroid insecticide, which has a good insecticidal effect on weevils and other insects that occur during the growth of Corydalis. The detection of deltamethrin in Corydalis is carried out

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Conclusion