Abstract
BackgroundThis study aims to report a case of rapid progression of cataract to mature stage after intravitreal dexamethasone implantation for macular edema due to branch retinal vein occlusion.Case presentationA 59-year-old Korean male with complaints of sudden metamorphopsia and reduced visual acuity for three days in the left eye was referred to our clinic. Ophthalmological investigations included fundus photography, fluorescein angiography, and optical coherence tomography. In the left eye, branch retinal vein occlusion with macular edema was observed. We performed intravitreal dexamethasone implantation in the left eye three times within a period of one year. One week after the third intravitreal dexamethasone implantation, grade 1 posterior subcapsular opacity and raised intraocular pressure were observed in the left eye. Three weeks later, mature cataract was observed in the left eye. We performed cataract surgery along with intravitreal ranibizumab injection in the left eye. The procedure was uneventful, and the visual acuity improved postoperatively.ConclusionsPosterior subcapsular cataract developed due to intravitreal dexamethasone implantation can progress rapidly to mature stage. Therefore, short-term follow-up examinations may be necessary for early diagnosis and treatment of this complication.
Highlights
This study aims to report a case of rapid progression of cataract to mature stage after intravitreal dexamethasone implantation for macular edema due to branch retinal vein occlusion.Case presentation: A 59-year-old Korean male with complaints of sudden metamorphopsia and reduced visual acuity for three days in the left eye was referred to our clinic
Branch retinal vein occlusion (BRVO) is the second most common retinal vascular disorder and a cause of visual loss due to macular edema (ME) and retinal ischemia. [1, 2] The pathogenesis of ME in BRVO is not fully understood; it may result from various causes such as an increase in cytokines and vascular endothelial growth factor (VEGF), [3] high hydrostatic pressure due to increased venous pressure, and dysregulation of endothelial tight junction proteins. [4]
We report a case of rapidly progressed cataract after intravitreal dexamethasone implant injection in a patient with ME with BRVO
Summary
Posterior subcapsular cataract developed due to intravitreal dexamethasone implantation can progress rapidly to mature stage.
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