Abstract
AbstractA simple copper catalyzed “one‐pot” process has been developed for synthesis of polysubstituted imidazoles via direct oxidative N‐α‐C(sp3)‐H functionalization of arylmethylamines. The readily available arylmethylamines as a substrate have afforded tetrasubstituted imidazoles products up to 94% yields under mild and environmentally benign conditions. The explored substrates scope with 1,2‐diketones and α‐hydroxyketones have shown great utility for synthesis of tetrasubstituted imidazoles.
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