Rapid Monitoring Method of Active and Passive Smoker with Saliva Continine by Gas Chromatrography-Mass Spectrometry

Abstract

Drug Abuse Research Center, Kongju National University, Kongju 314-701, KoreaReceived July 4, 2002Key Words : ETS monitoring, Cotinine, Saliva, GC-MSEnvironmental tobacco smoke (ETS) is the materialreleased into the ambient atmosphere by smoking tobaccoproducts, which consist of a heterogeneous mixture of gases,uncondensed vapors, tar and particle. ETS is a group Ahuman carcinogen as defined by the US EnvironmentalProtection Agency. Exposure to ETS is a cause of heartdisease and respiratory tract illness. Nicotine is the principalalkaloid in tobacco and is present as a major component oftobacco smoke. Nicotine is absorbed by both active andpassive smokers exposed to ETS, however, its short half-life(t