Abstract
Vancomycin overuse exerts a selective pressure for VRE and VISA and has been associated with poorer outcomes than beta-lactams when treating MSSA. Rapid determination of methicillin susceptibility should be particularly helpful to spare vancomycin in a setting where MRSA prevalence is low.
Highlights
Vancomycin overuse exerts a selective pressure for VRE and VISA and has been associated with poorer outcomes than beta-lactams when treating MSSA
MRSA was identified in 7 patients, MSSA in 46 and CNS in 36
PCR results were concordant with standard microbiological testing
Summary
Rapid determination of methicillin susceptibility should be helpful to spare vancomycin in a setting where MRSA prevalence is low
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