Abstract

A rapid test, utilizing latex particles (0.81-μm diameter), sensitized with Babesia argentina antigens, proved to be effective in the diagnosis of B. argentina in natural and experimental infections. Two drops of plasma or serum and one drop of B. argentina antigen placed on a glass plate were used in the test. Reaction was observed after 3—10 min rotation. The positive agglutination reaction was characterized by the formation of fine latex particle clumss. In experimental infections with B. argentina, the first detectable positive agglutination reactions coincided with the appearance of parasitemia in thin blood films. Plasma from animals with natural infections of B. argentina, proven by blood smears and indirect fluorescent antibody and complement fixation tests, also showed a reaction to the latex agglutination test.

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