Abstract
The rapid kinetics of depolarization-evoked calcium influxes in isolated nerve terminals from rat cortex were monitored by stopped-flow spectrofluorimetry using specific indicators (Fluo-3, Indo-1). A very rapid increase in the intrasynaptosomal Ca 2+-level was detected within the subsecond time range after depolarizing synaptosomes by mixing with physiological saline containing elevated K +-concentrations. About 15 mM [K +] o was determined as threshold concentration for inducing Ca 2+-influx, which increased with higher concentration and saturated at [K +] o-concentrations of about 40 mM [K +] o.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
