Abstract
Incidence of lymphogranuloma venereum increased in England during 2018–2019, after a period of decline. Our retrospective analysis of national surveillance data identified a rapid increase in diagnoses among HIV-negative men who have sex with men. These findings indicate a need for sustained surveillance and targeted public health action.
Highlights
Incidence of lymphogranuloma venereum increased in England during 2018–2019, after a period of decline
We show that a rapid increase occurred in Lymphogranuloma venereum (LGV) diagnoses in England in 2019, affecting men who have sex with men (MSM) who are HIV-negative or with unknown HIV status, such that nearly 60% of all LGV diagnoses are in this group
This trend represents a major shift in the epidemiology of LGV; infection was previously associated with MSM living with HIV [2]
Summary
We show that a rapid increase occurred in LGV diagnoses in England in 2019, affecting MSM who are HIV-negative or with unknown HIV status, such that nearly 60% of all LGV diagnoses are in this group. This trend represents a major shift in the epidemiology of LGV; infection was previously associated with MSM living with HIV [2]. An earlier decline in LGV diagnoses [9] has been attributed to revisions to LGV testing guidelines that led to expanded testing [5,12]. Use of HIV preexposure prophylaxis (PrEP) in England may have contributed to increased
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