Abstract

There is no doubt that animal experimentation plays a great part in the development of new thought in research medicine. One is, however, well acquainted with the shortcomings of observations so attained, when one attempts to duplicate the results in the clinic patient. It is therefore of ad vantage, whenever possible to illustrate certain phenomena through the use of the human subject. It has been possible to corroborate in a human control subject some observations previously made in the study of the effects of sex and growth in a group of boys to whom chorionic gonadotropin had been given (1). The observations reported herewith are particularly significant because the subjects were a set of identical twins who presented similar developmental defects in sex and growth and the observation period extended over a prolonged period of time.

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