Abstract
MANY WORKERS have repeated the observation by Aserinsky and Kleitman, in 1953,<sup>1</sup>of the cyclical recurrence of a physiologic state characterized by a low-voltage fast electroencephalogram (EEG), periodic bursts of rapid eye movements (REM), and a decrease in muscle activity.<sup>2</sup>Generally, there are four to five cycles per night and the predominance of slow-wave sleep in the first half of the night is followed by an increased incidence of REM periods during the last half of the night, in a pattern which is said to be fairly characteristic for a given individual.<sup>3,4</sup>The earlier studies of Dement and Kleitman,<sup>3</sup>as well as the more recent work of Williams et al,<sup>4</sup>have considered the REM cycle in relation to laboratory time, ie, time 0 is when the subject goes to bed and time is measured successively thereafter in terms of hours in the laboratory. The
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