Abstract

The conjugate addition of thiols to α, β-unsaturated carbonyl compounds was carried out rapidly (within 2–5 min) and selectively in the presence of silica supported sodium hydrogen sulfate (NaHSO4·SiO2) to form the corresponding Michael adducts in excellent yields (86–95%) at room temperature and under solvent-free conditions. †Part 157 in the series, ‘Studies on novel synthetic methodologies’

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