Abstract
Although extra pulmonary tuberculosis accounts for only 10-15% of tuberculosis in India, they have high morbidity and mortality because of lack of good diagnostic methods. One of the recent molecular methods namely the Xpert MTB/RIF is a fully automated real time PCR system that detects M. tuberculosis (Mtb) complex and rifampicin resistance directly from clinical samples. This assay has been extensively evaluated in the diagnosis of pulmonary tuberculosis. The purpose of this study was to test the efficiency of this assay for the rapid and reliable diagnosis of extra pulmonary tuberculosis (EPTB).
Highlights
Introduction extra pulmonary tuberculosis accounts for only 10-15% of tuberculosis in India, they have high morbidity and mortality because of lack of good diagnostic methods
One of the recent molecular methods namely the Xpert MTB/RIF is a fully automated real time PCR system that detects M. tuberculosis (Mtb) complex and rifampicin resistance directly from clinical samples. This assay has been extensively evaluated in the diagnosis of pulmonary tuberculosis
BMC Infectious Diseases 2012 12(Suppl 1):P32. Materials and methods This was a pilot prospective blinded study done on 60 samples received in the department of Microbiology from patients with signs and symptoms of extra pulmonary tuberculosis (EPTB)
Summary
Rapid diagnosis of extra pulmonary tuberculosis by automated Xpert MTB/RIF assay. Suzana, Baby Shalini, Priscilla Rupali, K Venkatesh, DJ Christopher, Joy S Michael*. From First International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2012) Chennai, India. From First International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2012) Chennai, India. 20-22 January 2012
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