Abstract
Blood stream infections and sepsis are major causes of hospitalization in most intensive care units around the globe, especially in developing countries like Nepal. Although the sepsis guidelines emphasize the role of early institution of appropriate antibiotics, it is practically challenging due to delayed turnover time of currently available diagnostic tests. Modifications in traditional blood culture methods, use of molecular techniques and availability of biomarkers have raised hope in rapid detection of blood stream infections.
Highlights
Less than one-tenth of hospital beds are occupied by critically ill patients in an intensive care unit (ICU), it accounts for more than a quarter of hospital acquired infections which carries a significant burden to both patients and the hospital in terms of hospital stay, morbidity, mortality and expense.[1]
This emphasizes the role of rapid microbiological diagnosis of infection in an ICU and this review tries to focus on some of the rapid diagnostic tools currently available
Fever and chills that are often associated with Catheter-related bloodstream infection (CR-BSI) are non-specific and local catheter site inflammation can occur without blood stream infection, has poor correlation with sensitivity of 3% or less
Summary
Less than one-tenth of hospital beds are occupied by critically ill patients in an intensive care unit (ICU), it accounts for more than a quarter of hospital acquired infections which carries a significant burden to both patients and the hospital in terms of hospital stay, morbidity, mortality and expense.[1]. This emphasizes the role of rapid microbiological diagnosis of infection in an ICU and this review tries to focus on some of the rapid diagnostic tools currently available
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