Year-end Sale % OFF 
Abstract
A new method has been developed for rapid identification of compounds in complex mixtures by gas chromatograph—mass spectrometer—computer system. The method uses a gas chromatographic retention index in conjunction with a small set of discriminating ions to identify each compound. The retention index predicts to within 1% the location of a time-dependent “window” within which a specific compound may appear, while the accuracy of the peak identification is dependent primarily upon the specificity of the ion set chosen. Optimum specificity is obtained by selecting ions which not only are chracteristic of the compound to be identified, but which also differentiate it from other compounds likely to elute at similar retention times. Utilizing the data files created by repetitive scanning during a single elution by gas-liquid chromatography, the present algorithm permits the automated identification of approximately eight compounds per minute. Examples of the identification of acidic urinary metabolites are given; however, the method is sufficiently general to be applied to any group of volatile compounds.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
