Abstract

The conventional method used for estimation of uranium (U) in bioassay samples takes nearly 4–5 days for complete sample analysis. In cases of incidental exposures, there is a need to reduce overall analysis time for the estimation of U in bioassay samples. Therefore, efforts were made in the present study to develop a comparatively rapid method for analysis of U in urine. For this purpose, a known amount of U(natural) standard was added to synthetic urine samples (1 L) and separated from by solid phase extraction chromatography using TRU resin (Eichrom Technologies, Inc.). The radiochemical yield recovery observed for U was 92.6% by this method. As a part of quality assurance, the method standardized in the present study was applied for estimation of U in urine samples collected from members of the public (MOP) and the results were compared to those previously obtained using ion exchange chromatography and fission track analysis (FTA).

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