Abstract
Rapid Clearance of Erythrodermic Psoriasis with Acitretin in an Unstable Case of Psoriasis under Treatment with Secukinumab
Highlights
S Erythrodermic Psoriasis (EP) is a rare, severe and disabling form of psoriasis in children and adults with an estimated prevalence among psoriatic patients ranging from 1%-2.25% [1]
Is not well understood; numerous studies advocate that the disease is associated with a predominantly T helper 2 (Th2)
The triggers of erythrodermic psoriasis are an abrupt extraction of anti-psoriatic drugs such as methotrexate and topical steroids, systemic illness (e.g. HIV, infections), ultraviolet burns, drug reaction, abuse of alcohol, and emotional stress [1,2]
Summary
(baseline PASI score 29.0), without concomitant arthritis, and was Erythrodermic Psoriasis (EP) is a rare, severe and disabling form of psoriasis in children and adults with an estimated prevalence among psoriatic patients ranging from 1%-2.25% [1]. This subtype successfully treated with secukinumab in the last year (PASI score 0). He did not have any other new drug exposures and did not use topical medications other than moisturizers, in the last 3 months of psoriasis presents with distinct clinical characteristics, which include a diffuse erythema involving at least 75% of the body surface area. The patient remains clear of psoriasis lesions with ongoing acitretin therapy after 16 weeks, with a tapering of acitretin while transitioning to the precedent biologic agent
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