Abstract
We have written a computer program (CRISTAL) by using PASCAL and PROLOG II to interpretate the crystallization database originally compiled by G. Gilliland and recently updated by us. A large repertoire of questions can be asked using natural language (English). Very rapid retrieval of crystallization data has been made possible thanks to the use of direct-access files and efficient coding of the key-words corresponding to the contents of the database. A brief statistical analysis is reported concerning the use of different precipitating agents and the publication trends between 1940 and May 1989. Finally, we mention the possible use of CRISTAL in the design of incomplete factorial experiments for macromolecule crystallization.
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