Abstract
AbstractA one‐pot tandem process involving hydrolysis, Knoevenagel condensation, Michael addition, and Conia‐ene (HKMC) reactions has been developed for the rapid synthesis of indanone‐fused 2‐methylene tetrahydrofurans from the reaction of enynals and propynols. In this process, two rings and four bonds are generated with 100 % atom‐economy and high step‐efficiency. The resulting tetrahydrofurans were readily oxidized into α‐methylene γ‐lactones, which are one of the most important substructures in natural and bioactive compounds.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
