Abstract
Follow-up of patients with gliomas remains a challenge in the field of neuro-oncology. The RANO group published its first follow-up criteria for high-grade gliomas in 2010. While it originally focused on clinical trials, it was also useful as a guide in clinical practice. They then went on to publish revised editions which included follow-up criteria for low-grade tumours, immunotherapy, and updates to the original criteria.In 2023, they published a more comprehensive guide, RANO 2.0, which included all glioma types and different treatments. For the first time, they considered the latest WHO classification and objective data in addition to expert opinion. RANO 2.0 establishes which type of MRI should be used for the baseline MRI, describes the different responses of contrast-enhanced and non-contrast-enhanced tumour components, and determines in what circumstances a confirmatory MRI is required.In light of these changes, it is worth reviewing these new criteria to enable a better understanding of the revisions and their applicability in routine radiological practice.
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