Abstract

The objective was to compare gamithromycin (GAM) and ceftiofur crystalline free acid (CCFA) metaphylaxis for controlling bovine respiratory disease (BRD) impacts in auction market-derived steers. Steers (n=240; initial BW = 537.54 ± 60.61 lb [243.82 ± 27.49 kg]) were randomly allocated to 16 pastures randomized to the 2 treatment groups. Caretakers and data analyst were masked to treatments. Data were analyzed using linear models with means ( ± standard errors of means) reported. Following metaphylaxis, 16 steers (GAM, n=3; CCFA, n=13) required treatment for BRD. Mean BRD morbidity was higher (P=0.03) in the CCFA group (10.83 ± 2.84%) compared to the GAM group (2.50 ± 1.43%). Four steers in each group died or were removed from the 59-day trial due to non-BRD health reasons. Average daily gain in steers finishing the study was greater (P=0.03) in GAM (2.90 ± 0.09 lb [1.32 ± 0.04 kg]) vs CCFA (2.57 ± 0.09 lb [1.17 ± 0.04 kg]) steers. Mean net return per head for steers finishing the study was greater (P≤0.01) for GAM ($22.34 ± 6.75) vs CCFA (-$6.67 ± 6.75). Overall, steers administered GAM metaphylaxis had lower morbidity, increased weight gain, and increased net revenue, compared to those given CCFA.

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