Abstract

The aim of this study was to assess the efficacy of Normast 300 mg in reducing swelling and pain after the surgical extraction of impacted lower third molars. Materials and Methods. A randomized, split-mouth, single-blind study was conducted on 30 patients between 18 and 30 years of age requiring lower third molar extraction. Patients underwent bilateral extractions in a randomized sequence, one extraction being performed under Normast treatment. The Normast treatment involved 2 tablets a day for 15 days. The parameters assessed at each procedure were trismus, swelling, pain, NSAID consumption, postoperative complications, drug tolerability, and safety. The results obtained were processed using repeated measures analysis of variance. Results. Perceived postoperative pain was reportedly significantly milder on Normast treatment than control. The trend of the means differed over time (P < .0001) and between the two extraction groups (P < .0221). On the other hand, for edema and trismus, the trend differed over time for both groups but did not differ between the two groups. Discussion. Our analyses indicate that patients experienced significantly less postoperative pain when they were treated with Normast. Conclusions. Administering Normast improves the postoperative course—in terms of pain—after lower third molar extraction.

Highlights

  • The third molars, and those of the mandible in particular, are the most frequently impacted of all teeth, with an incidence ranging between 9.5% and 39%, depending on the source considered [1].Impacted third molar extraction is a common procedure in oral and maxillofacial surgery [2,3,4,5,6,7,8,9,10], but third molar surgery is associated with an incidence of intraoperative and postoperative complications in the range of 4.6% to 30.9% [4]

  • The results showed that the means for postoperative pain, mouth opening range, and the distance between the labial commissure and the tragus changed significantly with time, irrespective of the Normast treatment or any of the other explanatory variables

  • Patients complain of pain, swelling, and trismus as the main factors negatively influencing their quality of life [3, 11] after surgery for lower third molar extraction

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Summary

Introduction

Impacted third molar extraction is a common procedure in oral and maxillofacial surgery [2,3,4,5,6,7,8,9,10], but third molar surgery is associated with an incidence of intraoperative and postoperative complications in the range of 4.6% to 30.9% [4]. Patients complain of pain, swelling, and trismus being the factors that most negatively affect their quality of life [3, 11] in the postoperative period. The aim of the present study was to assess the efficacy of Normast 300 mg in reducing postoperative pain and swelling after surgery to extract impacted lower third molars.

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