Abstract

Objective To study the effects of nitroglycerin on improving the microcirculation in patients with septic shock. Methods A total of 27 patients with septic shock from February 2015 to February 2016 were randomly divided into nitroglycerin group(14 cases) and control group(13 cases). The general data, acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ), sepsis related organ failure assessment(SOFA), central venous pressure(CVP), mean arterial pressure(MAP), cardiac index(CI), hemoglobin, arterial oxygen saturation(SaO2), central venous oxygen saturation(ScvO2), Lactate, urine volume were compared between the two groups. Results Compared with control group, in nitroglycerin group, the APACHE Ⅱ decreased, SOFA decreased, MAP raised, ScvO2 decreased, Lactate decreased, urine volume raised(P<0.05). Conclusion Nitroglycerin can improve the microcirculation and outcomes in patients with septic shock. Key words: Nitroglycerin; Septic shock; Microcirculation; Oxygen delivery; Hemodynamics

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.