Abstract
Gall bladder cancer is generally fatal. The high morbidity and mortality due to gall bladder cancer exerts a significant impact on efforts towards cancer control in high risk populations of the World and a rationale program for control of gall bladder cancer mortality has remained as an unmet need in these populations. Currently there are no effective strategies for controlling gall bladder cancer mortality. This mini review is to highlight the need and feasibility for secondary prevention of gall bladder cancer by screening in high risk populations. A way forward is to assess the role of secondary prevention of gall bladder cancers by conducting randomized- controlled screening trials in high risk populations.
Highlights
Gall bladder cancer (GBC) is the most common malignancy that arises from the biliary tract
There is no randomized-controlled screening trial that has been conducted to see the role of screening in lowering GBC mortality
If the cases of incidental GBC can be identified by a screening radiological suspicion followed by its surgical removal, the mortality due to it can be reduced
Summary
Gall bladder cancer (GBC) is the most common malignancy that arises from the biliary tract. There are no effective strategies for controlling gall bladder cancer mortality. This mini review is to highlight the need and feasibility for secondary prevention of gall bladder cancer by screening in high risk populations.
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