Abstract
BackgroundRalstonia mannitolilytica is an emerging opportunistic pathogen that is associated with severe disease, including septic shock, meningitis, and renal transplant infections. Reports on this pathogen are limited, however, especially on the African continent.Case presentationA 2-year-old Akan child was presented to a hospital in the northeastern part of Ghana with a 1-week history of fever and chills. We identified Ralstonia mannitolilytica in her blood culture using both conventional and 16S ribosomal deoxyribonucleic acid (rDNA) techniques. The patient’s condition improved clinically upon treatment with cefuroxime.ConclusionOur report highlights the potential of Ralstonia mannitolilytica to cause sepsis and thus emphasizes the need for improved laboratory diagnosis and evidence for use of appropriate antibiotics in rural settings of Africa, where presumptive treatment using antimicrobial agents is rife.
Highlights
Ralstonia mannitolilytica is an emerging opportunistic pathogen that is associated with severe disease, including septic shock, meningitis, and renal transplant infections
Ralstonia mannitolilytica (R. mannitolilytica) is another emerging opportunistic pathogen within the nonfermenting gram-negative bacillus group that is present in both hospital and environmental settings [1]
R. mannitolilytica had previously been referred to as “Pseudomonas thomasii” and R. pickettii biovar 3/“thomasii” [2]. Clinical infections with this pathogen are rare, disease progression to severity tends to be more serious once individuals are exposed
Summary
Our report highlights the potential of Ralstonia mannitolilytica to cause sepsis and emphasizes the need for improved laboratory diagnosis and evidence for use of appropriate antibiotics in rural settings of Africa, where presumptive treatment using antimicrobial agents is rife.
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