Abstract

Ralstonia mannitolilytica is an emerging opportunist pathogen reported in many healthcare facilities over the years. We report a case with R. mannitolilytica bacteraemia in breast carcinoma patient with chemo port. Identification of this non fermentative, Gram negative bacilli was done by Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI TOF MS). A minireview of cases of R. mannitolilytica bacteremia in the recent years with special reference to those reported in India is done.

Highlights

  • The genus Ralstonia comprises a group of non-fermentative, Gram-negative bacteria (NFGN) found in moist environments, such as water, soil, and plants [1]

  • We report a case with R. mannitolilytica bacteraemia in breast carcinoma patient with chemo port

  • A minireview of cases of R. mannitolilytica bacteremia in the recent years with special reference to those reported in India is done

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Summary

INTRODUCTION

The genus Ralstonia comprises a group of non-fermentative, Gram-negative bacteria (NFGN) found in moist environments, such as water, soil, and plants [1]. CASE A 38 years old female patient was admitted with history of one day high grade fever She was a diagnosed case of a right sided carcinoma breast stage II and had undergone modified radical mastectomy six months before. Two sets of blood cultures were taken from the peripheral vein and chemo port. She was put on Piperacillin-tazobactam empirically, but fever spikes persisted. The differential time to positivity (DTP) between blood taken from chemo port and the peripheral vein was 6 hours 35 minutes. Glucose was oxidized, urea was hydrolysed and nitrates were not reduced to nitrites It was presumptively reported as Gram negative Nonfermenter as it was unidentified by Vitek 2 (bioMérieux, France). All microbiological data of hospital were reviewed, but no Ralstonia spp. have been matched in the last two years

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