Rainfall accumulation as a driver of higher Leptospirosis risk in northern South America

Abstract

Rainfall accumulation during wet seasons in Northern South America can be enhanced during La Niña ENSO phases.  Leptospirosis is a zoonotic waterborne disease that affects humans, domestic animals, and wildlife associated with occupational and recreational water activities, natural disasters, and socioeconomic conditions for which rainfall plays a key role in its transmission. We analyzed the incidence of leptospirosis, and relative risk of changes on the incidence of the disease due to rainfall accumulation in Northern Colombia during the period 2007-2021. The rainfall accumulation analysis was done for 7, 14 and 21 days based on the periods of incubation of the disease, biology of transmission, and thresholds of rainfall accumulation above the mean values. We found a statistically significant association between excess rainfall and leptospirosis at different lags for cities in Northern Colombia (Barranquilla, Santa Marta, Cartagena) and the levels of accumulated rainfall exceedance associated with leptospirosis were specific for each city. Our findings give insight into the association between leptospirosis and excess accumulated rainfall and provide climate services and local health authorities with tools to act on and prevent this important zoonotic disease.