Abstract

Fowler model for NEffective tumor clonogens number in Biological Effective Dose (BED) algorithms constrained to head and neck cancer is simulated. RT biological models provide with a dose delivery radioprotection optimal minimization of photon-dose deposition while keeping the most efficacious dose to maximize Tumor Control Probability in head and neck tumors. Results comprise the Effective Clonogens model for head and neck cancer parameters 3D Graphical Optimization simulations. 3D imaging results for NEffective (Effective Tumor Population Clonogenes Number) determination after passing on the standard radiotherapy treatment time are shown. RT applications for TPO in head and neck cancer with Fractionation-dose are explained.

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