Radioterapia intraoperatoria de electrones en cáncer de mama. Experiencia en Venezuela.

Abstract

Objective: To evaluate the evolution of patients treated with intraoperative electron radiotherapy by Group J Soteldo, in Hospital de Clínicas Caracas. Methods: Descriptive observational study. We included 18 patients treated with intraoperative electron radiation therapy between April 2017 and July 2018. Medical records were reviewed to study the evolution, patients who had not returned in the last six months were contacted by telephone. Intraoperative electron radiation therapy was applied during the same surgical act, at a dose of 21 Gy, after the tumor was removed from the affected breast, at the level of the tumor bed. Results: The mean age was 54.5 years, the mean tumor size was 2.48 cm. Twelve patients had cancer in the right breast (66.7%) and six in the left (33.3%). Nine cases (50%) were Luminal B; 15 patients had infiltrating ductal carcinoma (83.3%), 13 (72.2%) had a negative axilla. Six patients (33.3%) underwent axillary dissection up to the third level and 12 (66.7%) had a sentinel node. Five patients (27.8%) received a single dose of intraoperative electron radiation therapy and 13 (72.2%) received booster doses. No patient has had a relapse of the disease or serious adverse effects associated with radiation therapy. Conclusion: The use of intraoperative electron radiation therapy was an effective and well tolerated treatment in this group of patients. It is not a commonly used treatment in Venezuela. Key words: Breast cancer, Radiotherapy, Electrons.