Abstract
Stereotactic surgery destroys or affects small intracranial targets and it can be carried out with a number of different physical agents: heat or cold, chemical or radioactive solutions, radioactive sources, ultrasound or laser beams. In all these cases, the physical agent is carried to the target through a burr hole. Leksell, 1951, had the idea of using stereotactically directed narrow ionizing beams which can reach the target through the intact skull. He coined the term radiosurgery. We define radiosurgery as a neurosurgical procedure where narrow ionizing beams, given in a single high dose fraction, are used either to destroy a predetermined target volume or to induce a desired biological effect in the target volume without opening the skull and with minimum risk of damage to the surrounding non target neural tissue.
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