Abstract
Several biologic characteristics may be utilized in making the choice of treatment by radiotherapeutic or surgical modalities. A test dose of radiation (RST) enables us to discriminate between good responders in Stages I and II with an expected relative cure rate of 72.1 per cent under those with poor response whose relative cure rate declines to 32.5 per cent under the same radiotherapeutic treatment. Another group with poor response subjected to radical surgery achieved a relative cure rate of 56 per cent. Tumor virulence has also been assayed by recording lymphatic invasion in the control biopsies. The validity of age and geographic tumor configuration as measures of tumor virulence were not established. A protocol of individualized treatment for cervix cancer, based on these considerations, is presented.
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