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Abstract
Radioprotective oral appliances can be used during radiotherapy (RT) to prevent radiation-induced oral complications. Three women and 2 men with squamous cell carcinoma (SCC) of the lip (T1-T2N0M0), age 46 to 72 years, were eligible for curative RT with electron beam (60 to 66 Gy) and the use of personalized radioprotective oral appliances. Patients were evaluated before, during, and after RT for xerostomia and mucositis with scales (Eisbruch et al and World Health Organization). One patient complained of mild oral dryness that did not interfere with function; the others showed no xerostomia. Except for the tumor margins, protected areas of the oral mucosa showed no radiation mucositis, nor did patients experience taste alterations. The oral appliances prevented unnecessary irradiation of normal tissues, thus reducing the risk of morbidity in the form of mucositis and osteoradionecrosis. Treated patients had no signs of recurrence. Acknowledgment: FAPEMIG.
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