Abstract

Sophisticated radionuclide imaging techniques are providing greatly improved estimates of the extent of cardiac damage and coronary artery involvement in persons who have suffered their first myocardial infarction. In a presentation to the recent meeting of the American Federation for Clinical Research in Washington, DC, cardiologist Randolph E. Patterson, MD, of the Mount Sinai School of Medicine in New York, reported that imaging with thallium 201 identified three-vessel and left main coronary artery disease more accurately during exercise than did electrocardiography or the occurrence of angina. Patients with these forms of ischemic heart disease are most likely to benefit from coronary artery bypass operations, he pointed out. In a separate presentation, Edward Geltman, MD, assistant medical director of the Cardiac Diagnostic Laboratory at Washington University School of Medicine in St Louis, showed that tomographic scanning using positron-emitting isotopes accurately identified the location and size of infarct zones in affected

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