Abstract

BackgroundRadiological examinations of COVID-19 positive patients play a vital role in early diagnosis and assessment of disease course, as most COVID-19 infected patients were diagnosed with pneumonia and characteristic CT imaging patterns. Asymptomatic infected individuals, called “asymptomatic carrier or transmitter”, who are the infectious sources of SARS-CoV-2, and some of them progress rapidly, even resulting in acute respiratory distress syndrome (ARDS) with a high case-fatality rate. Our study is a prospective study and aims to be familiar with the CT imaging features of asymptomatic cases with COVID-19 pneumonia.ResultsA total of 44 asymptomatic cases with COVID-19 pneumonia between March 20, 2020 and May 23, 2020 were enrolled. All patients had a history of exposure to SARS-CoV-2 or recent travel history. All patients had no symptoms. The predominant feature of CT findings in this cross-sectional study was ground-glass opacity (GGO) (41, 93%) with peripheral (34, 77.3%) distribution, bilateral location (20, 45.5%) with lower lobe predominance (left lower lobe 72% and right lower lobe 50%).ConclusionCT imaging of asymptomatic cases with COVID-19 pneumonia has highly characteristics findings. Since asymptomatic patients are the asymptomatic transmitter, and some patients can progress rapidly in the short term, it is essential to early diagnose asymptomatic patients with COVID-19. CT scan has great sensitivity in screening and detecting patients with COVID-19 pneumonia.

Highlights

  • Radiological examinations of COVID-19 positive patients play a vital role in early diagnosis and assessment of disease course, as most COVID-19 infected patients were diagnosed with pneumonia and characteristic Computed tomography (CT) imaging patterns

  • Radiological examinations are vital in early diagnosis and assessment of disease course, as most COVID-19 infected patients were diagnosed with pneumonia and characteristic CT imaging patterns [3]

  • The aims of our study are to understand the imaging spectrum of asymptomatic COVID-19 positive patients and to facilitate the detection and isolation of asymptomatic patients who act as the asymptomatic transmitter of the disease. Patients This cross-sectional study included 44 asymptomatic patients (16 males, 28 females) with an age range from 8 to 66 years, who were not yet diagnosed as asymptomatic corona patients; after imaging, they were confirmed to be infected with SARS-CoV-2 using reverse transcriptase-polymerase chain reaction (RT-Polymerase chain reaction (PCR)) test, they were referred for Multi-slice computed tomography (MSCT) assessment of the chest for different causes (Table 1)

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Summary

Introduction

Radiological examinations of COVID-19 positive patients play a vital role in early diagnosis and assessment of disease course, as most COVID-19 infected patients were diagnosed with pneumonia and characteristic CT imaging patterns. Asymptomatic infected individuals, called “asymptomatic carrier or transmitter”, who are the infectious sources of SARS-CoV-2, and some of them progress rapidly, even resulting in acute respiratory distress syndrome (ARDS) with a high case-fatality rate. Radiological examinations are vital in early diagnosis and assessment of disease course, as most COVID-19 infected patients were diagnosed with pneumonia and characteristic CT imaging patterns [3]. Asymptomatic infected individuals, called “asymptomatic carrier or transmitter”, may become the contagious source of SARS-CoV-2, and some of them progress rapidly, even resulting in acute respiratory distress syndrome (ARDS) with a high case-fatality rate [4, 5].

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