Abstract
Cushing's syndrome of obesity, hypertension, weakness and depression of sexual function, is associated with over-production of the adreno-cortical steroids, particularly cortisone and hydrocortisone. These excess steroids are produced as a result of hyperplasia or neoplasia of the adrenal cortex. The literature of the radiological changes encountered in the skeleton in this condition is reviewed. The main radiological changes include: 1. Osteoporosis of a widespread nature, which is more easily demonstrated in the axial than in the appendicular skeleton. 2. Pathological fractures, which may occur anywhere in the weakened skeletal structures, but are most commonly seen in the spine, ribs and pelvis. 3. Abnormal callus formation, having a “cotton-wool” appearance, develops round these fractures and in particular appears to be responsible for the sign of marginal condensation, described in connection with crush fractures of vertebral bodies. This calcification represents an incomplete attempt at fracture hea...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
