Abstract
The objective of the present study is to evaluate bone loss at implant abutments coated with a soda-lime glass containing silver nanoparticles subjected to experimental peri-implantitis. Five beagle dogs were used in the experiments, 3 implants were installed in each quadrant of the mandibles. Glass/n-Ag coted abutments were connected to implant platform. Cotton floss ligatures were placed in a submarginal position around the abutment necks and the animals were subject to a diet which allowed plaque accumulation, and after 15 weeks the dogs were sacrificed. Radiographs of all implant sites were obtained at the beginning and at the end of the experimentally induced peri-implantitis. The radiographic examination indicated that significant amounts of additional bone loss occurred in implants without biocide coating, considering both absolute and relative values of bone loss. Percentages of additional bone loss observed in implants dressed with a biocide coated abutment were about 3 times lower (p<0.006 distal aspect; and p<0.031 at mesial aspect) than the control ones. Within the limits of the present study it seems promising the use of soda-lime glass/nAg coatings on abutments to prevent peri-implant diseases.
Highlights
Peri-implantitis is a common biological complication in implant therapy and a main cause of implant failure [1,2,3,4]
Concerning peri-implantitis some strategies have been developed in recent years [9]: On the one hand, efforts have been made in prevention of bone loss around implants-new implant designs have been commercialized seeking to reduce bone remodeling after osseointegration as well as modern implantabutment connection minimizing bacterial filtration- due to the impossibility of completely eliminating bacterial contamination, subgingival plaque formation is still a problem which often result in peri-implantitis; on the other hand, treatment remains based on mechanical debridation, antibiotic treatment and osseous regeneration when possible
The clinical examinations performed at the initial weeks of the experimental induced peri-implantitis revealed important gingival inflammation around the biocide coated abutments and no changes in the control implants
Summary
Peri-implantitis is a common biological complication in implant therapy and a main cause of implant failure [1,2,3,4]. Findings from experiments in the dog and the monkey have demonstrated that submarginal plaque formation induced by ligature placement results in peri-implant tissue breakdown [6,7]. Morse cone-connection) minimizing bacterial filtration- due to the impossibility of completely eliminating bacterial contamination, subgingival plaque formation is still a problem which often result in peri-implantitis; on the other hand, treatment remains based on mechanical debridation, antibiotic treatment and osseous regeneration when possible. It seems that the eradication of resistance is impossible and development of resistance to any particular antibiotic is inevitable
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