Abstract
Iron absorption and the effective utilization of an absorbed tracer dose of radioiron were determined in normal subjects and in patients with idiopathic hemochromatosis, before and during venesection therapy. Radioactive sodium chromate was used as a marker in the absorption study. Iron absorption was normal or marginally increased in idiopathic hemochromatosis before venesection therapy, whereas it was shown by Bothwell and Finch 17 that increased iron stores in the body decreased iron absorption in cases without hemochromatosis. During venesection therapy, iron absorption is greatly increased. This may be due to active erythropoiesis after venesection or to an unmasking of increased rate of iron absorption in idiopathic hemochromatosis. The effective utilization of the absorbed radioiron for red cell formation was very low in idiopathic hemochromatosis, and sodium chromate was found to be a useful marker in normal subjects, but was partially absorbed in cases of hemochromatosis during venesection therapy.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
