Abstract
SummaryA sensitive and specific radioimmunoassay for 8-hydroxyadenine has been developed. As little as 4 × 10−14 moles of 8-hydroxyadenine can be detected. Unmodified DNA cross-reacts only at concentrations greater than 20 μg/ml. 8-hydroxyadenine can be detected in γ-irradiated DNA at doses less than 10 Gy. The assay requires only mild chemical treatment and many samples can be quickly and easily handled.
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Schedule a callMore From: International journal of radiation biology and related studies in physics, chemistry, and medicine
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