Abstract
Editor's Note.-Articles in the RadioGraphics Update section provide current knowledge to supplement or update information found in full-length articles previously published in RadioGraphics. Authors of the previously published article provide a brief synopsis that emphasizes important new information such as technological advances, revised imaging protocols, new clinical guidelines involving imaging, or updated classification schemes. Articles in this section are published solely online and are linked to the original article.
Highlights
Our previously published educational article, “Contrast-enhanced US Approach to the Diagnosis of Focal Liver Masses,” describes a practical algorithmic approach to imaging liver lesions with contrast agent–enhanced US (CEUS) [1]
Many LR-3 nodules are followed closely so that they may be monitored for progression along the pathway of hepatocarcinogenesis, as determined by changes in size or enhancement characteristics
The changes in blood flow help explain why hepatocellular carcinoma (HCC) and its precursors can exist in the absence of arterial phase hyperenhancement (APHE), and this is shown in CEUS Liver Reporting and Data System (LI-RADS) (Figs 3, 4)
Summary
Our previously published educational article, “Contrast-enhanced US Approach to the Diagnosis of Focal Liver Masses,” describes a practical algorithmic approach to imaging liver lesions with contrast agent–enhanced US (CEUS) [1] It focuses on the evaluation of all nodules in all adult patients. In this update, we expand and focus our algorithm to include the assessment of nodules in patients at risk for hepatocellular carcinoma (HCC) to incorporate the wide range of nodules that arise during hepatocarcinogenesis, the process whereby benign nodules in the liver transform from regenerative nodules to dysplastic nodules and eventually HCC. We describe the varied enhancement patterns reflecting blood supply changes as nodules progress through hepatocarcinogenesis and correlate these changes with their CEUS LI-RADS categories
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
