Abstract

The main objective in the use of radioactive colloidal gold for the treatment of cancer of the cervix is safe, adequate, and convenient irradiation of the pelvic lymph nodes. This is in no way different from the motive behind the use of conventional x-rays, supervoltage x-rays, or the gamma rays of radium or cobalt. The treatment of the primary lesion is no problem. Supplemental therapy is necessary, however, because some patients undoubtedly have cancer in the pelvic lymph nodes which would not be destroyed by direct irradiation of the cervix or by hysterectomy. Radiogold is only an agent for providing supplemental therapy. The properties of radiogold are nearly ideal for this purpose. The short half-life of 2.8 days limits the duration of irradiation. The radioactivity is primarily beta, so that the majority of the effect is restricted to the immediate vicinity of the interstitial injection. Radiogold, however, is especially valuable because of the manner in which the tissues absorb and “fix” the gold. ...

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